diseases

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Engineered microglia show promise for treating Alzheimer’s and other brain diseases

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer’s disease and other neurological…

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Health

Towards gene-targeting drugs capable of targeting brain diseases

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine’s most difficult challenges, limiting our ability to…

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Health

Treatment for mitochondrial diseases within reach

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular…

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Health

New gene editing tool shows promise for treating diseases with multiple mutations

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that…

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Health

Genetic predisposition to sedentary behavior increases the risk of cardiovascular diseases

Although sedentary behaviour may be an evolutionarily selected trait, it is still important to try to be physically active, says…

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Health

A gentle approach offers new hope for inflammatory lung diseases

Pulmonary sarcoidosis is a lung disease characterized by granulomas — tiny clumps of immune cells that form in response to…

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Health

Enzyme engineering opens door to novel therapies for Parkinson’s, cancers and other hard-to-target protein diseases

Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson’s…

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Health

Fatty liver linked to increased risk of death from several diseases

A comprehensive study from Karolinska Institutet shows that people with fatty liver disease have almost twice the mortality rate of…

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Health

Treating chronic inflammatory diseases with JAK inhibitors

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis,…

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Health

Scientists gain insight into RNA-editing protein that could lead to improved treatment for cancer, autoimmune diseases

A research team led by Rice University’s Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a…

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