inhibitors

Health

Discovery suggests opportunity to improve effectiveness of KRAS inhibitors against pancreatic cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS…

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Health

The body’s own lipids affect mental disorders: Can specific inhibitors help?

A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and…

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Health

Easing Tamoxifen, Aromatase Inhibitors’ Side Effects for Breast Cancer Treatment

Many people who’ve had breast cancer take medications – tamoxifen or aromatase inhibitors – to help prevent the cancer from…

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Health

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists at Duke-NUS Medical School have uncovered why some pancreatic and colorectal cancers[1] fail to respond to Wnt inhibitors, a…

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