mutations

Health

Early mutations and risk factors for stomach cancer, and develops a pre-cancer model for stomach cancer prevention

Researchers from the Department of Pathology, School of Clinical Medicine at the LKS Faculty of Medicine of the University of…

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Study sheds light on how inherited cancer mutations drive tumor growth

Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor…

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New gene editing tool shows promise for treating diseases with multiple mutations

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that…

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How a small number of mutations can fuel outbreaks of western equine encephalitis virus

New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts…

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Pancreatic cells ‘remember’ epigenetic precancerous marks without genetic sequence mutations

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal…

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Researchers identify mutations that can lead to resistance to some chemotherapies

Investigators at Mass General Brigham have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a…

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Genetic mutations linked to toxin exposure found in firefighters’ brain tumors

Occupational and environmental exposures can put specific groups of people at higher risk of cancer, including firefighters. A new study…

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New technique reveals how the same mutations give rise to very different types of leukaemia

Myeloid leukaemias are among the most aggressive blood cancers and have low survival rates. Today, leukaemia patients undergo genetic analysis…

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‘Perfect storm’ of mutations drives infection-triggered autoimmune disease

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing…

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DNA damage can last unrepaired for years, changing our view of mutations

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA…

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