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Distinct T-cell signatures observed at different stages of type 1 diabetes development

A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from…

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Health

‘Goldilocks’ binding strength determines anti-cancer T-cell efficacy and fate

Immunotherapy, treatments that reinvigorate immune cells’ anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating…

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Health

Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another…

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Health

Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets

Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T-cell immunotherapy,…

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Health

Investigators develop novel treatment for T-cell leukemias and lymphomas

A novel treatment for leukemias and lymphomas that arise from immune system T cells, developed by investigators at the Johns…

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Health

CAR T-Cell Therapy: Who Might Benefit?

Chimeric antigen receptor (CAR) T-cell therapy is a new way to treat cancer. It’s a living drug made from T…

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