therapies

Health

Largest osteoarthritis genetic study uncovers pathways to new therapies and repurposed drugs

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis,…

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Health

Immunotherapy Drug Spares Cancer Patients From Grisly Surgeries and Harsh Therapies

When a person develops solid tumors in the stomach or esophagus or rectum, oncologists know how to treat them. But…

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Health

Enzyme engineering opens door to novel therapies for Parkinson’s, cancers and other hard-to-target protein diseases

Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson’s…

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Health

Study unravels mystery of cancer-fueling enzyme–could lead to new therapies

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell…

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Health

FLIpping the Switch: Boosting stem cell numbers for therapies

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce…

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Health

New genetic risk score identifies individuals at risk for heart disease who may benefit most from cholesterol-lowering therapies

Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout…

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World

A new switch for the cell therapies of the future

The body regulates its metabolism precisely and continuously, with specialised cells in the pancreas constantly monitoring the amount of sugar…

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Health

Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and…

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Health

The secret life of ALAS1: How a basic science discovery could pave the way for better siRNA therapies

In everyday life, when things turn out the opposite of what you expect, it’s usually cause for frustration. In science,…

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Health

Unlocking worm strategies: A path to innovative vaccines and therapies

A research team led by Prof. Julia Esser-von Bieren from the Center of Allergy and Environment (ZAUM) at Helmholtz Munich…

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